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energy transfer) gamma- and X -ray irradiations . These models are most relevant to the dose rates healthy tissue is exposed to during such radiotherapy procedures as the Gamma Knife ( 29 ). ‘ High -LET ...
during late gestation/lactation, the total dose administered to the dam was 2 μg/kg. Regardless of these subtle differences, the most striking effect of developmental exposure was observed in offspring ...
benzene exposure despite the significant genotoxicity of benzene even at low doses both in experiments and in epidemiology? Second, why is there no linear increase in incidence at high - dose exposure despite ...
architecture. The thymic -dependent pathway relies on an adequate supply of progenitors able to home to the thymus and able to effectively proliferate and differentiate. The differences observed in this study ...
), recipient mice were lethally X - irradiated with 2 doses of 5.5 Gy with a 4 h interval between each dose of radiation. During the 4 h interval, pregnant dams were euthanized and c112K fetuses were removed ...
effects or non-specific signals. Altogether, these data show that F5 thymocytes are synchronously and specifically activated by the cognate peptide addition to thymic slices, leading to rapid changes ...
of age have a high probability of thymic rebound while late thymic recovery has been detected in patients up to 50 years of age [1, 2]. ROLE OF THE THYMUS IN T-CELL DIFFERENTIATION The thymus, derived from ...
depleting antibodies [43] and focused high - dose irradiation of the thymus [44]. A myriad of subsequent regimens combined low- dose TBI or TLI with high - dose thymic irradiation and depleting monoclonal ...
mechanistic insights toward explaining estrogen action on thymocyte development, selection, and maturation, as well as the effects of genistein on prenatal and neonatal thymic development and function. immune ...
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