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Background/Aims: Human bone-marrow mesenchymal stem cells (hBMSCs) are widely transplanted into inflammatory microenvironment to accelerate tissue regeneration. Transplanted hBMSCs recruit host ...
Abstract: Mesenchymal stem cells are clonogenic, non‐haematopoietic stem cells present in the bone marrow and are able to differentiate into multiple mesoderm‐type cell lineages e.g. osteoblasts ...
Hematopoietic stem cell transplantation (HSCT) is an effective treatment for many malignant hematological diseases. Mesenchymal stem cells (MSCs) are nonhematopoietic stem cells with strong self ...
cells . After miR-124-transfected bone marrow-derived mesenchymal stem cells were transplanted into the injured rat spinal cord, a large number of cells positive for the neuronal marker neurofilament-200 ...
later would be called a “ mesenchymal stem cell ” or MSC. Over the years, it has become progressively clear that such cells , which can differentiate in vitro into a variety of mesenchymal lineages ...
the properties and potential utilization of mesenchymal stem cells (MSCs) have aroused considerable interest and expectations. Biological characteristics of MSCs, including multi-lineage differentiation , homing ...
embryonic stem cells ; (2) autologous and heterologous mesenchymal stem cells ; and (3) implants of xenografts, more differentiated autologous cells , or unfractionated mononuclear bone marrow cells . The human ...
Mesenchymal stromal cells (MSCs) are multipotent stem cells able to differentiate into mesenchymal origin tissue and support the growth of hematopoietic stem cells . In order to understand the role ...
vasculature. However, the lack of sufficient transplantable cells before the deterioration of disease condition is a current limitation to apply cell therapy in patients. It is necessary to differentiate ...
. Serial transplantation experiments performed in the fumarylacetoacetate hydrolase (FAH)–deficient mice have underlined not only the extraordinary replication capacity of these differentiated cells but also ...
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