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to those of native spiral ganglion neurons were identified. These cells showed neuron -specific voltage- and time- dependent currents and exhibited two distinct firing patterns similar to those seen in rodent ...
the assessment of agents that functionally impair sensory neurons . Cell-based model systems for the PNS are still mostly based on non-human cells, like rat dorsal root ganglion (DRG) neurons . Such DRG cultures ...
. NGF is not only a key mediator of embryonic development and for the maintenance of specialized properties of sensory neurons , but it also has a variety of neurotrophic and nonneurotrophic functions ...
surface, with its innervating sensory neuron is shown. The nucleus of the neuron has been enlarged to depict the intranuclear events occurring during lytic and latent infection. Figure 3. Open in new ...
Immunohistopathological studies of patients with PNS have also demonstrated CD3+ and CD8+ T-lymphocyte predominant infiltrates in brain or dorsal root ganglia which supports cytotoxic T-cell- mediated neuronal loss, rather ...
(4): 736–747). Our further analyses on orco mutant ants reveal differential dependence of orco in the development and survival of odorant receptor neurons (ORNs). Interestingly, although male ...
constitutive neurogenesis throughout the mammalian lifespan. The OE is comprised of multiple cell types including olfactory sensory neurons (OSNs) that are readily replaced by two populations of basal stem cells ...
, such as the dependence on aerobic metabolism for a constant oxygen supply, the presence of axonal transport, or the processes of neurotransmission.11 A neurotoxic effect can be the direct alteration of the neuronal ...
sensory neurotoxicity varies from paresthesia in fingers to ataxic gait, which might be transient or irreversible. Because the number of patients being treated with these neurotoxic agents is still ...
, channel, antioxidant, and other pathways. A 24-hour treatment with lipopolysaccharide (200 μg/mL) and interferon-γ (10 μg/mL) was used to induce inflammation and study molecular signaling, flow- dependent ...
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