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the use of methylphenidate hydrochloride or atomoxetine hydrochloride reduces the risk of injuries among children and adolescents with ADHD. DESIGN, SETTING, AND PARTICIPANTS We used the German ...
) has been demonstrated in children , adolescents , and adults [ 1, 2 ]. It was approved in the USA in 2002 for the treatment of ADHD. Atomoxetine is predominantly metabolized by cytochrome P450 2D6 (CYP2D6 ...
program, January 1, 2002, through September 30, 2005. Participants A mean of 405 000 children and adolescents aged 2 to 17 years qualified each month. Main Exposure Piecewise linear regression models were ...
reportedly suffer from increased mortality [35,36] and, whilst studies investigating hospitalisation and mortality in children and adolescents are rare, increased psychiatric hospitalisation [37] and mortality ...
agonist both dispensed twice or more over 1 year), epilepsy (BNF section 4.8), ADHD (methylphenidate hydrochloride , dexamphetamine sulphate, atomoxetine , or lisdexamfetamine dimesylate), depression ...
of the Chief Medical Examiner (NC OCME) toxicology laboratory, one of the active metabolites, threobupropion, is used as a complementary indicator for the extent of exposure to the parent compound. Metabolite ...
). Drugs Methylphenidate hydrochloride (MPH; Rubio laboratories) was dissolved in saline (0.9% solution of NaCl) and administered intraperitoneally (i.p.). In microdialysis experiments, MPH (1 and 3 mg/kg ...
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