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ABSTRACT Objective: In young rats, skeletal muscle arterioles respond to acetylcholine, which elicits Ca2+‐dependent endothelial nitric oxide (NO) release , but not to shear stress, which does ...
modulation of the nitric oxide release pattern. Analysing calcium dependent and independent regulation of eNOS in endothelium triggered by extracellular signalling events N. T. Devikaa and B. M. Jaffar Ali*b ...
Release of nitric oxide (NO) from endothelial cells critically depends on a sustained increase in intracellular free calcium maintained by a transmembrane calcium influx into the cells. Therefore, we ...
calcium followed by relaxation. The oleanolic acid‐evoked endothelium‐derived NO release was independent of endothelial cell calcium and involved phosphoinositide‐3‐kinase‐dependent phosphorylation of Akt ...
See related article, pages 870–877 A New Paradigm Calcium Independent and Caveolae Internalization Dependent Release of Nitric Oxide by the Endothelial Nitric Oxide Synthase Ghassan Bkaily, Pedro ...
calcium antagonist), and sodium nitroprusside (which liberates nitric oxide from its molecular struc ture) as EDRF- independent pharmacological probes in rat ...
Both endothelial nitric oxide synthase (type III) and neuronal nitric oxide synthase (type I) are activated when calmodulin is bound to the enzyme by increases in intracellular calcium . The third isoform ...
Several peptides, including vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), activate the release of arachidonic acid (AA) and nitric oxide (NO) in endothelial ...
Nitric Oxide Regulation of Myocardial Contractility and Calcium Cycling Independent Impact of Neuronal and Endothelial Nitric Oxide Synthases Shakil A. Khan,* Michel W. Skaf,* Robert W. Harrison ...
focus on preserving or restoring endothelial integrity. Whereas nitrates partly substitute deficient endogenous nitric oxide , calcium antagonists counteract angiotensin II and endothelin-1 at the level ...
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