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function in a variety of acquired conditions that impair concentrating ability including some nephrotoxic agents. Renal Failure, 21(3&4), 331-336 (1999) Aquaporin - 2 as a Biomarker of Distal Renal Tubular ...
is a distal tubule and collecting duct toxicant. Segment specificity for the lesions was shown using a newly developed triple IHC combination method with antibodies against calbindin D28, aquaporin 2 ...
for other tubular segments were measured by real-time qPCR. Subsequently, renal protein levels of NCC, PV, aquaporin 1 and aquaporin 2 were determined using immunoblotting and immunohistochemistry (IHC ...
kidney injury and the subsequent loss of kidney function after cardiac surgery. These findings highlight DKK3 as a mediator of renal tubular cell damage in kidney injury and short-term progression ...
ischemia-reperfusion: biases and myths-the proximal vs. distal hypoxic tubular injury debate revisited . Kidney Int 77 : 9 – 16 , 2010 . OpenUrl CrossRef Medline Web of Science 14. ↵ Huber O , Korn R ...
for severity. The area under the receiver operating characteristic (ROC) curve was used to compare the diagnostic accuracy of each exploratory renal biomarker with traditional indicators of renal function ...
increase the expression of the aquaporin - 2 water channels and the epithelial sodium channels in the distal part of the nephron using biomarkers for the activity of the two channels. Methods. We performed ...
Abstract Drug-induced kidney injury (DIKI) is a major concern in both drug development and clinical practice. There is an unmet need for biomarkers of glomerular damage and more distal renal injury ...
in identifying active crescentic ANCA-GN. In Stage II, UAGT decreased after immunotherapy and increased at the time of renal relapse during the 2 -year follow-up, suggesting the usefulness of UAGT to monitor ...
, translocation of aquaporin - 2 , cytoskeletal reorganization and molecular transport in rat inner medullary collecting duct cells.28,29 Primary human kidney proximal tubular epithelial cells also have been studies ...
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