“Woah! It's like Spotify but for academic articles.”

Instant Access to Thousands of Journals for just $40/month

Get 2 Weeks Free

Antidiarrhoeal Activity of Diterpenes of Andrographis paniculata (Kal-Megh) against Escherichia coli Enterotoxin in in vivo Models

Antidiarrhoeal Activity of Diterpenes of Andrographis paniculata (Kal-Megh) against Escherichia coli Enterotoxin in in vivo Models

Abstract

The alcoholic extract of Andrographis paniculata exhibited significant antidiarrhoeal activity against E. coli enterotoxins in animal models. The activity was further located in n-butanol fraction, which led to the isolation of four diterpenes, andrographolide (7), neoandrographolide (2), deoxyan-drographolide (3), and andrographiside (4). Among the four diterpenes, andrographolide and neoandrographolide showed similar activity to loperamide against E. coli LT and LT/ST enterotoxins. Andrographolide was found to be superior against ST enterotoxin, the most common cause of epidemics of neonatal diarrhoea.
Loading next page...
Problems Reading this Article? Report Issue Here
 
/lp/informa-healthcare/antidiarrhoeal-activity-of-diterpenes-of-andrographis-paniculata-kal-LkkADSy0MW

You're reading a free preview. Subscribe to read the entire article.

And millions more from thousands of peer-reviewed journals, for only $40/month.

Get 2 Weeks Free

To be the best researcher, you need access to the best research

  • With DeepDyve, you can stop worrying about how much articles cost, or if it's too much hassle to order — it's all at your fingertips. Your research is important and deserves the top content.
  • Read from thousands of the leading scholarly journals from Springer, Elsevier, Nature, IEEE, Wiley-Blackwell and more.
  • All the latest content is available, no embargo periods.

Stop missing out on the latest updates in your field

  • We’ll send you automatic email updates on the keywords and journals you tell us are most important to you.
  • There is a lot of content out there, so we help you sift through it and stay organized.