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for metastatic breast cancer. Phase I studies have indicated that the maximum tolerated dose of paclitaxel given by 24-h infusion every three weeks is 175-200 mg/m2 without G-CSF support and 200-250 mg/m2 with G ...
: Results of a phase I study The Oncologist 2010 15 1198 – 1204 Google Scholar Crossref Search ADS PubMed WorldCat 37 Pawlik TM , Reyes DK, Cosgrove D et al. Phase II trial of sorafenib combined ...
function [62]. The first phase I study in patients with advanced solid tumors reported a good tolerability of tozasertib up to doses of 8 mg/m2/hour, when administered by continuous 5-day intravenous ...
achieved using CHOP [54]. More recently, pralatrexate was evaluated in combination with the CHOP regimen in previously untreated patients with PTCL in a 3 + 3 phase I dose ‐escalation study . The MTD ...
stakeholders with chronic pain and substance use disorder to understand and mitigate fear that the study intervention could interfere with access to opioid prescriptions. The pre-implementation phase of this PCT ...
as the baseline value for sequential monitoring. In children with suspected AHO, we suggest against using serum procalcitonin (PCT) (conditional recommendation and low certainty of evidence). II. What imaging ...
), or neural lineage cells derived from bone marrow MSC (1 trial), and 16/19 studies were performed in dogs. The MSC studies (13/17) used adipose tissue-derived MSC from either allogeneic (8/13) or autologous (5 ...
imputed using the average SDs of similar studies in the meta-analysis. Moreover, carry-over effect and intracluster correlation coefficient (ICC) was considered for data imputation when cross-over ...
in GBM tissue samples to confirm our findings in a clinical context. The aforementioned studies will be instructive for understanding the dimerization behavior of oncogenic EGFRs in GBMs and will use ...
(CON) at 1400 to 1500 h for 21 d. The dose was administered orally in 5 mL of diluted corn syrup using a calibrated dosing gun. The treatment was targeted to begin at the start of the follicle phase ...
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