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of the components are fully additive. This analysis provides guidance for dosing . Aim. To describe the antihypertensive dose – response of combination therapy with candesartan and hydrochlorothiazide (HCT). Patients ...
candesartan cilexetil, irbesartan, losartan or valsartan, alone or in combination with hydrochlorothiazide . There were no significant differences in BP responses between recipients of the 4 different AIIAs ...
of life of the new angiotensin II type 1 (AT1) receptor blocker candesartan cilexetil, the angiotensin-converting enzyme inhibitor enalapril, and the diuretic hydrochlorothiazide (HCTZ). Women, aged 40 ...
hours after single dosing with candesartan a clinically relevant rightward shift in the angiotensin II dose - response curve (DR = 3.2) occurred that was more pronounced than that following losartan ...
Abstract The aim of the study was to compare the efficacy and tolerability of candesartan cilexetil (C)with an angiotensin-converting enzyme inhibitor therapy (A), with the addition ...
, and candesartan when administered at their recommended doses . These four AIIA also show a near-flat dose - response curve when administered at doses recommended for the treatment of hypertension, which suggests ...
interactions. Various dosage regimens of telmisartan and hydrochlorothiazide were incorporated into the traditional indirect response models, and simulations were performed at different dose levels. Simulations ...
at intermediate risk without cardiovascular disease to candesartan 16 mg/ hydrochlorothiazide 12.5 mg or placebo and rosuvastatin 10 mg or placebo. The first co-primary outcome was a composite of cardiovascular ...
, randomized, double-blind comparison of candesartan cilexetil (8 mg), enalapril (10 mg), and placebo, with groups unbalanced 2:2:1 in patient numbers, and with the possibility to add hydrochlorothiazide (12.5 ...
analysis still demonstrated the greatest BP response to thiazide diuretics as compared to candesartan or beta blockers, regardless of APOL1 genotype. Our identification of CSMD1 and DPP6 as possible ...
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