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, and/or multipotency. In recent years, proteomic approaches have produced a wealth of data identifying proteins and mechanisms involved in SC proliferation and differentiation. Although many proteomics techniques have ...
Abstract Stem cells are essential for maintaining tissue homeostasis and mediating physiological and pathological regeneration. Recent breakthroughs in stem cell biology have generated tremendous ...
-consuming, and technically daunting. Another study by Chua et al . recently demonstrated the development of organoids from sorted luminal cells, but these 3D cultures with a limited growth potential [71 ...
cardiology, the last three decades were marked by several major breakthroughs in the treatment for acute myocardial infarction (AMI), such as the introduction of the coronary care unit, pharmacological ...
processes are not completely dissolved yet. Recent in vitro and in vivo research identified some key molecules scattered light on the extravasation mechanism. This review provides a detailed overview over ...
to further breakthroughs in the clinical application of neural stem and progenitor cells. In this review, we discuss the functions of adult-born DG neurons, describe the epigenetic regulation of adult DG ...
myocardium, leading to cardiac functional improvements [37, 38]. A recent study by Tachibana et al . found that transplantation of ESC-/iPSC-CMs exhibited ventricular functional improvements, accompanied ...
to specific treatment strategies, as was indicated in a recent study that showed concordant results for pharmacological response between iPSCs and a patient with type 3 long QT syndrome (Malan et al ., 2016 ...
-based and technical compliant mechanisms, is presented in Poppinga et al . (2016b). In the following, we highlight recent developments and breakthroughs and address persisting challenges in the field ...
of motor neurons potentially available for autologous transplantation [83, 84]. Moreover, a recent study by Chou et al . [85] has successfully established a method to generate integration-free human iPSCs ...
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