Donor lymphocytes infusions (DLI) represent a possible way to induce graft-versus-leukemia (GVL) effect in patients that relapse after allogeneic hematopoietic stem cell transplantation (HSCT). We and others previously described that the subpopulation of CD4+CD25+ immunoregulatory T cells (Treg) could play a key role in the control of alloreactive responses.
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