Reflections on a Path to Sexual Commitment Thomas W. Cline 1 Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3204 1 ↵ Address for correspondence: Department of Molecular and Cell Biology, 16 Barker Hall, Mail Code 3204, University of California, Berkeley, CA 94720-3204. E-mail: sxlcline@uclink.berkeley.edu Next Section Anecdotal, Historical and Critical Commentaries on Genetics Edited by James F. Crow and William F. Dove IT was with some self-consciousness that I accepted an invitation to reflect on my own work, a long G enetics article that appeared 20 years ago entitled, “Autoregulatory Functioning of a Drosophila Gene Product That Establishes and Maintains the Sexually Determined State” ( C line 1984 ). This article was a milestone in a line of work that began with an intriguing maternal effect and led ultimately to an understanding of the fly's sex-determination signal and the self-propagating response of that signal's target. The invitation to reflect on that 1984 article has given me an opportunity to make more explicit the lines of argument that I had not always made clear, writing at a time when authors stressed data presentation and expected readers to infer more of the logic and significance of
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