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First Individual Diploid Human Genome Published By Researchers at J. Craig Venter Institute. Sequence Reveals that Human to Human Variation is Substantially Greater than Earlier Estimates. Press Release: September 3, 2007 (1) This theory suggests that only the differentiating cells will inherit the newly “photocopied” DNA strands, which contain errors. The stem cells retain the unmodified original DNA strands, which consequently remain “immortal” after repeated cell divisions. G. Cossu, S. Tajbakhsh Cell, 2007 (2) The capacity to blunder slightly is the real marvel of DNA. Without this special attribute, we would still be anaerobic bacteria and there would be no music. Lewis Thomas “The Medusa and the Snail”, 1979 (3) DNA STRIKES BACK When news arrived that the 2007 Nobel Prizes for Medicine or Physiology had been awarded to Mario Capecchi, Martin Evans, and Oliver Smithies for targeting genes in mice, it crowned the comeback of DNA (4). For two 0892-6638/07/0021-3773 © FASEB decades now, fans of RNA have been lording it over those who study its deoxygenated sibling. Ever since Wally Gilbert announced the “RNA world” (5), and Sidney Altman and Thomas Cech discovered its enzymatic properties (6), RNA has been flying high. First, RNA interference (RNAi)

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Mortal and Immortal DNA: Craig Venter and Keats’ "Lamia"

Gerald Weissmann
The FASEB Journal , Volume 21 (14): 3773
Fed of American Socs for Experimental BiologyDec 1, 2007

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