First Individual Diploid Human Genome Published By Researchers at J. Craig Venter Institute. Sequence Reveals that Human to Human Variation is Substantially Greater than Earlier Estimates. Press Release: September 3, 2007 (1) This theory suggests that only the differentiating cells will inherit the newly âphotocopiedâ DNA strands, which contain errors. The stem cells retain the unmodiï¬ed original DNA strands, which consequently remain âimmortalâ after repeated cell divisions. G. Cossu, S. Tajbakhsh Cell, 2007 (2) The capacity to blunder slightly is the real marvel of DNA. Without this special attribute, we would still be anaerobic bacteria and there would be no music. Lewis Thomas âThe Medusa and the Snailâ, 1979 (3) DNA STRIKES BACK When news arrived that the 2007 Nobel Prizes for Medicine or Physiology had been awarded to Mario Capecchi, Martin Evans, and Oliver Smithies for targeting genes in mice, it crowned the comeback of DNA (4). For two 0892-6638/07/0021-3773 © FASEB decades now, fans of RNA have been lording it over those who study its deoxygenated sibling. Ever since Wally Gilbert announced the âRNA worldâ (5), and Sidney Altman and Thomas Cech discovered its enzymatic properties (6), RNA has been ï¬ying high. First, RNA interference (RNAi)
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