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Journals Journal of Leukocyte Biology Volume 86 Issue 4

Adaptive immune responses are critical for the control and clearance of influenza A virus (IAV) infection. However, in recent years, it has become increasingly apparent that innate immune cells, including natural killer cells, alveolar macrophages (aMφ), and dendritic cells (DC) are essential following IAV infection in the direct control of viral replication or in the induction and regulation of virus-specific adaptive immune responses. This review will discuss the role of these innate immune cells following IAV infection, with a particular focus on DC and their ability to induce and regulate the adaptive IAV-specific immune response.

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Innate immune control and regulation of influenza virus infections

McGill, Jodi; Heusel, Jonathan W.; Legge, Kevin L.
Journal of Leukocyte Biology , Volume 86 (4): 803
Fed of American Socs for Experimental Biology – Oct 1, 2009

More Info
  • Publisher Society for Leukocyte Biology
  • Copyright Copyright © 2009 by the Federation of American Societies for Experimental Biology
  • ISSN 0741-5400
  • D.O.I. 10.1189/jlb.0509368
  • Publisher site Get PDF  

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