Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines 1 JESANG KO * ,† ,2 , SUNG-WUK JANG * , YOON SUK KIM * , IN SIK KIM ‡ , HO JOONG SUNG ‡ , HONG-HEE KIM § , JOONG-YEOL PARK † , YOUNG HAN LEE †† , JIYOUNG KIM ‡‡ and DOE SUN NA ‡ * Asan Institute for Life Sciences, Departments of † Internal Medicine and of ‡ Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, Korea; § Department of Cell and Developmental Biology, College of Dentistry, Seoul National University, Seoul, Korea; †† Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, Daegu, Korea; and ‡‡ Graduate School of Biotechnology, Kyung Hee University, Yongin, Korea 2 Correspondence: Asan Institute for Life Sciences and Department of Internal Medicine, University of Ulsan College of Medicine, Seoul 138-736, Korea. E-mail: jesangko@amc.seoul.kr <h3>SPECIFIC AIMS</h3> LZIP, a transcription factor in various cell types, was identified as a CCR1 binding protein. The aim of this study was to confirm the interaction between CCR1 and LZIP and to characterize the regulatory function of LZIP in chemokine-induced cell migration during inflammatory cellular processes. <h3>PRINCIPAL
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Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines
KO, JESANG; JANG, SUNG-WUK; KIM, YOON SUK; KIM, IN SIK; SUNG, HO JOONG; KIM, HONG-HEE; PARK, JOONG-YEOL; LEE, YOUNG HAN; KIM, JIYOUNG; NA, DOE SUN
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, Volume 18 (7): 890
Fed of American Socs for Experimental Biology – May 1, 2004
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