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Previously, α-MSH, a 13-amino acid neuropeptide and the tripeptide α-MSH have been shown to possess potent antimicrobial properties. We performed microplate based growth inhibition assays on C. albicans with α-MSH, but could not observe any growth inhibiting effect. Repeating the originally published assay with different C. albicans strains, we detected a mild growth inhibiting effect of 100 μM α-MSH, but again no effect of α-MSH.

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Anti-Candida activity of α-melanocyte-stimulating hormone (α-MSH) peptides

Rauch, Isabella; Holzmeister, Simone; Kofler, Barbara
Journal of Leukocyte Biology , Volume 85 (3): 371
Fed of American Socs for Experimental BiologyMar 1, 2009

More Info

  • Publisher Society for Leukocyte Biology
  • Copyright Copyright © 2009 by the Federation of American Societies for Experimental Biology
  • ISSN 0741-5400
  • D.O.I. 10.1189/jlb.1008614
  • Publisher site Get PDF  

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