Previously, α-MSH, a 13-amino acid neuropeptide and the tripeptide α-MSH have been shown to possess potent antimicrobial properties. We performed microplate based growth inhibition assays on C. albicans with α-MSH, but could not observe any growth inhibiting effect. Repeating the originally published assay with different C. albicans strains, we detected a mild growth inhibiting effect of 100 μM α-MSH, but again no effect of α-MSH.
/lp/fed-of-american-socs-for-experimental-biology/anti-candida-activity-of-melanocyte-stimulating-hormone-msh-peptides-dLM1L8u3wj