A “simple” method for spurious biostatistics: response to the manuscript submitted to The FASEB Journal by Hudes, et al . Palaninathan Varalakshmi 1 , Chinnakannu Panneerselvam and Dhanapal Sakthisekaran Department of Medical Biochemistry, ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, India 1 Correspondence: Department of Medical Biochemistry, ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113 Tamil Nadu, India. E-mail: drvlakshmi@yahoo.com lipoic acid oxidative stress antioxidants aging data variability data manipulation the authors (hudes , et al .) of the manuscript have chosen to cluster together three distinct research groups of three senior scientists with different objectives and capabilities. The manner in which the published articles have been selected for analysis appears quite casual. Broad similarities such as “oxidative stress” or “rats” are hardly adequate for a meaningful comparison when there are so many distinguishing parameters in biomedical experiments. An unreasonable pooling of heterogeneous biochemical experimentations in terms of animal models (species, age, sex, body weight, number of animals in each group), pathologies, treatment groups, types of biochemical analyses, assay protocols, instrumentation, etc ., have been attempted by the authors, claiming to have developed a “simple
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A “simple” method for spurious biostatistics: response to the manuscript submitted to The FASEB Journal by Hudes, et al.
Varalakshmi, Palaninathan; Panneerselvam, Chinnakannu; Sakthisekaran, Dhanapal
Follow The FASEB Journal
, Volume 23 (3): 704
Fed of American Socs for Experimental Biology – Mar 1, 2009
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