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Journals Cancer Letters Volume 314 Issue 2

Highlights ► VEGF-D was expressed in all three GBC cell lines (GBC-SD, NOZ, and SGC-996). ► VEGF-D-RNAi-LV inhibited NOZ cells proliferation and invasion in vitro. ► VEGF-D-RNAi-LV inhibited tumor growth and lymphatic metastasis in xenograft model. ► VEGF-D-RNAi-LV inhibited tumor ascites and hepatic invasion in xenograft model. ► VEGF-D may be a potential molecular target in the treatment of GBC.

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Vascular endothelial growth factor-D promotes growth, lymphangiogenesis and lymphatic metastasis in gallbladder cancer

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  • Publisher Elsevier
  • Copyright Copyright © 2011 Elsevier Ireland Ltd
  • ISSN 0304-3835
  • D.O.I. 10.1016/j.canlet.2011.09.004
  • Publisher site Get PDF  

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