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of lingual sensory innervation is conveyed via TG afferents in the lingual nerve terminating in the anterior two-thirds of the tissue, whereas the posterior one-third is innervated by the glossopharyngeal ...
acid amides, such as sanshool, elicit numbing and tingling sensations by inhibiting 2-pore-domain potassium leak channels on trigeminal sensory neurons. Even when insufficient to induce action potential ...
potentiation, we performed two selective nerve block experiments in 30 healthy male volunteers. Functional blockade of TRPV1-positive nociceptors by high-concentration capsaicin (verified by loss of heat pain ...
, Patapoutian A . Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo . Neuron 21 : 325 – 334 , 1998 . OpenUrl CrossRef ...
)-signaling through the TrkB receptor is one of many mechanisms likely involved in this process. Specifically, BDNF produced by taste receptor cells functions via TrkB present in nerve fibers to encourage fiber ...
, 1998 . OpenUrl Abstract / FREE Full Text 5. ↵ Abdulla FA , Smith PA . Nociceptin inhibits T-type Ca 2+ channel current in rat sensory neurons by a G-protein-independent mechanism . J Neurosci 17 : 8721 ...
. TRAM-34 (40 mg/kg i.p. every 12 hours for 7 days) prevented this autism- like behavior and restored normal preference for social novelty compared to untreated controls (p=0.032). The same animals ...
(Supplementary Fig. S5C–C″). Barrelette organization was spared in both RORαTh and RORαCtx mice (Supplementary Fig. S5D–D″) indicating that trigeminal sensory input is not modified in both conditional KO models ...
is controversial since most patients are infants. However, the fact that long-term survivors, especially in older patients, were more likely to have had initial radiation favors the use of radiotherapy ...
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