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386 Obstetrical and Gynecological Survey disease. The drug appeared to be well-tolerated However, in women for whom estrogen therapy and, after treatment for 6 months, was associ- is not an option ...
disodium, the “mother compound” for modern-day bisphosphonates, was first used in the treatment of osteoporosis . The cyclic use of etidronate in therapy , which is known mainly to specialists in the field ...
bisphosphonates reduce the rates of fractures due to osteoporosis , recent reports suggested a link between bisphosphonate use and the development of atypical insufficiency fractures. This is thought to be due ...
Purpose The risks and benefits of long-term bisphosphonate therapy were reviewed. Summary Bisphosphonates are used first line in the treatment of osteoporosis due to their demonstrated ability ...
). No subject had received drug therapy for osteoporosis in the past. TABLE 1. Baseline characteristics of women with osteoporosis treated with alendronate alone (group 1), teriparatide alone (group 2), or both ...
studies assessing osteoporosis medications included calcium and vitamin D as background therapy . Thus, for patients with osteoporosis or who are at high risk of developing osteoporosis (e.g., patients ...
any bone mass lost since the adult peak was attained. In the general and the IBD populations, the risk factors for developing low bone mass, characterized either as osteoporosis or osteopenia, for both ...
or treatment of osteoporosis in other high-risk populations (e.g., postmenopausal women, patients with glucocorticoid-induced osteoporosis ), and many of these therapies have been evaluated in CTIBL patients ...
persist in the bone matrix for years, even after therapy is discontinued, potentially resulting in fetal bisphosphonate exposure during pregnancy. Adverse effects of bisphosphonates on fetal outcomes have ...
. (Although tiludronate does not contain an amino terminal group, it is considered second generation because of the timing of development and potency.) Even more potent are agents containing a tertiary nitrogen ...
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