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a variety of glutamate receptors mediating these responses. OFF ‐bipolar cells express ionotropic glutamate receptors (iGluRs) that are directly activated by glutamate or the glutamate agonists, kainate and α ...
Abstract Animal ionotropic glutamate receptors (iGluRs) are ligand-gated channels whose evolution is intimately linked to that of the nervous system, where the agonist glutamate and co-agonists ...
contraction, silkworm Glutamic acid functions as a neurotransmitter in the mammalian central nervous system (CNS) (1–3), where it activates both ionotropic and G-protein–coupled metabotropic receptors , and has ...
by vanilloid or ionotropic glutamate receptor antagonists, suggesting that it was mediated by a retrograde messenger acting at an AM251-sensitive, noncannabinoid/nonvanilloid receptor at presynaptic GABA ...
, which results in a lowering of the membrane potential. The ionotropic glutamate receptors are further divided into the subtypes 2-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), N-methyl-d ...
, evolved from ionotropic glutamate receptors (iGluRs) and are thus called Variant Ionotropic Receptors , or simply Ionotropic Receptors (IRs) [24–27]. The iGluRs form tetrameric ion channels, with each ...
-it experiments are inconclusive. Ionotropic glutamate receptors , also found on HC dendrites, can also suppress feedback [30]. This could constitute an alternative pathway for current flow from HCs, perhaps ...
29.3 ± 10.7 to 26.4 ± 12.3 pA, n = 7, P = 0.45) or cells from the dehydrated group (89.2 ± 14.4 to 83.7 ± 17.9 pA, n = 6, P = 0.47), indicating that it was not mediated by ionotropic glutamate receptor ...
ionotropic glutamate receptors (AMPARs). The mutation (A653T) falls within the highly conserved transmembrane domain of the ion channel gate, immediately adjacent to the analogous residue in the Grid2 ...
ionotropic glutamate receptors (iGluRs) function as Glu-activated ion channels that mediate most excitatory neurotransmission in the brain (Dingledine et al., 1999). The three pharmacologically defined classes ...
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