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The tumor microenvironment (TME) plays a vital role in tumor invasion and metastasis and provides a rich environment for identifying novel therapeutic targets. The TME landscape consists ...
Inflammatory cells and mediators are essential components in tumor microenvironment and play decisive roles in the initiation, proliferation, survival, promotion, invasion, or metastasis of lung ...
Lung metastasis is the leading cause of breast cancer -related death. The tumor microenvironment contributes to the metastatic colonization of tumor cells in the lungs . Tumor secretory factors ...
As an important medium of intercellular communication, exosomes play an important role in information transmission between tumor cells and their microenvironment . Tumor metastasis is a serious ...
are microRNAs, which are associated with tumor progression and metastasis in lung cancer . Although research into exosome-derived microRNA (exosomal miRNAs) is still in its early stages, it holds promise ...
player in tumor lung metastasis by affecting the host microenvironment . These findings could provide a sound theoretical basis for clinical treatment. Background: Metastasis is the primary cause of cancer ...
BackgroundBreast cancer lung metastasis occurs in more than 60% of all patients with breast cancer , and most of those afflicted by it eventually die of recurrence. The tumor microenvironment plays ...
Myeloid-derived suppressor cells (MDSCs) are key immunosuppressive cells in the tumor microenvironment (TME) that play critical roles in promoting tumor growth and metastasis . Tumor -associated ...
microenvironment is in a state of immune tolerance and suppression, which is beneficial to tumor development and metastasis . The lung tumor microenvironment is a more complex system that further enhances ...
in the lung than in the liver. Our results demonstrate that the intravascular microenvironment is a critical staging area for the development of metastasis that later can invade the parenchyma. Intravascular ...
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