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, which had morphologic features of activation . huGFAP‐CCL2hi tg+ mice lacking CC chemokine receptor 2 (CCR2) were normal, showing that chemokine action via CCR2 was required. Studies of cortical slice ...
autoimmune encephalomyelitis.J Exp Med.2000;192:899-906.LIziksonRSKleinIFCharoHLWeinerADLusterResistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR) 2 .J Exp Med ...
cells and the extracellular matrix engage pattern recognition receptors on microglia (II), resulting in the latter’s activation . Blood products leaked into the circulation during primary injury (I) also ...
, function, and expression in activated T‐lymphocytes. J Exp Med 1996 a; 184 : 963 –9. Loetscher P, Seitz M, Baggiolini M, Moser M. Interleukin‐ 2 regulates CC chemokine receptor expression and chemotactic ...
the recent advances made, by our scientists and elsewhere, in unraveling disease mechanisms, including the role of chemokines and their receptors in the neuropathogenesis of HIV-1 encephalitis. Mononuclear ...
in vivo. The contribution of MSC-borne chemokines , CCL2 in particular, and the recently recognized biological role of CC /CXC chemokine heterodimers found in MSC secretome as potent agents of immune ...
Addison, C.L., Daniel, T.O., Burdick, M.D., Liu, H., Ehlert, J.E., Xue, Y.Y., Buechi, L., Walz, A., Richmond, A., and Strieter, R.M. ( 2000 ) The CXC chemokine receptor 2 , CXCR2, is the putative receptor ...
a major role in the migration of monocytes and T cells, we here investigated the expression of the CC chemokines MIP-1α, MIP-1β, and RANTES in brain tissue from MS patients using reverse transcriptase ...
immune responses [5]. During viral infection activated microglia respond through a highly regulated network of cytokines and chemokines , which subsequently recruits the peripheral leukocytes into the CNS ...
of chemokine receptors , classical monocytes migrate in response to the CC - chemokine ligand (CCL)- 2 and macrophage inflammatory protein-1α (MIP-1α) also known as CCL3.24,25 In addition, the classical monocytes ...
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