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in populations with high African ancestry , like Rio de Janeiro and Salvador, and with TB in Mozambique. T/G/G (rs1052176/rs4971072/rs11264359) haplotype drives the susceptibility association with mycobacterial ...
ER , Zaitlen N , Daya M , et al. Genome-wide association study of ancestry -specific TB risk in the South African coloured population . Hum Mol Genet 2014 ; 23 ( 3 ): 796 – 809 . Google Scholar Crossref ...
genetic heterogeneity in the CMA ethnicity, we included a set of 96 Ancestry Informative Markers (AIMS) for the complex five-way admixed South African Coloured population as described previously [28, 30, 37 ...
WorldCat 22. Daya , M. , van der Merwe , L., Gignoux , C.R., van Helden , P.D., Möller , M. and Hoal , E.G. ( 2014 ) Using multi-way admixture mapping to elucidate TB susceptibility in the South African ...
, which has been previously described [6,11,12,16]. All individuals belonged to the South African Coloured group, a unique multi-way admixed population [46]. There was no specific requirement for subjects ...
to efficiently measure genetic diversity and global ancestry of DataMed-indexed cohorts and summarize and index the results through a diversity score (DS). The role of race and ethnicity in disease etiology has ...
) with sub-Saharan Africans and Europeans have shaped a distinctive genetic makeup that likely affects disease susceptibility and health disparities. Based on single nucleotide polymorphism array data ...
(PRS) to benchmark the generalizability of published findings to our VA patient population. Noting the appreciable representation of African ancestry (AA) participants in CSP #572 and drawing upon ...
an important role in the gene expression dynamics. In prisons or other environments with a high burden of TB , being in contact with a case may go unnoticed. Still, other factors, such as overcrowding and long ...
, their frequencies and linkage disequilibrium (LD) pattern vary among populations. In South Asians, both variants are of low frequency (MAF 4%) and present strong LD (r2 = 1), while in American and African populations ...
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