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in S.cerevisiae. It has been demonstrated that derepression of PHR1 enhances light - dependent repair of UV -induced DNA damage (25). Therefore, it is of interest to investigate the relationship between the DNA-damage ...
transcripts were induced after DNA-damaging treatments such as high intensity light , UV -C and γ-radiation. The yeast two-hybrid assay detected a strong interaction between OsMus81 and OsRad54 recombinational ...
includes two mitoses, with H1 kinase activity peaks at 20 and 140 min. These results indicate that the UVDE activity increase in response to UV light depends on UV –induced damage and not cell cycle phase ...
affecting overall repair and survival, would not affect up-regulation of RAD51. In conclusion, we have shown that up-regulation of RAD51 is not dependent on the primary damage or on the cell cycle response ...
study we reported that a rhp51Δ mutant of the fission yeast S.pombe showed sensitivity not only to the DNA‐damaging agents methyl methanesulfonate (MMS) and UV light , but also to caffeine, which overrides ...
). These RAD54 foci are dependent on the activation of the DDR pathway, and co-localized with phophorylated H2AX (γ-H2AX) signals, which are usually associated with damaged DNA. Moreover, in living cells , RAD54 ...
-ray irradiation cells were irradiated in tissue culture medium at a dose rate of 2.8 Gy/min (200 kV, 4 mA, 1 mm Al). For irradiation with UV light of 254 nm, a Philips TUV germicidal lamp was used ...
al., 2004). In addition, Shaked et al. (2006) showed that 14 of the 40 Arabidopsis SWI2/SNF2 gene family members also had a role in DNA damage response against γ or UV -C radiation and recombination ...
- dependent response (Fig 1A). Flow cytometry data analysis revealed a positive correlation between elevated ROS and the increased PI fluorescence. This finding was further confirmed by fluorescence microscopy ...
, supporting a role for homologous recombination (HR) in genome stability under nondamaging conditions. In addition, Ylrad52 mutants showed moderate to high sensitivity to UV light , oxidizing agents ...
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