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Journals Current Opinion in Immunology Volume 23 Issue 5

Highlights ► This review focuses on ubiquitin and the role of E3 enzymes that attach it to substrates in regulating TNF signalling. ► This review highlights the results from mice that have components of the TNF signalling complex knocked out. ► Recently described types of ubiquitin modification in TNF signalling such as K11- and linear ubiquitin chains are discussed. ► New models of TNF signalling based on recent research and analysis in this review are proposed.

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The regulation of TNF signalling: what a tangled web we weave

Silke, John
Current Opinion in Immunology , Volume 23 (5)
Elsevier – Oct 1, 2011

More Info
  • Publisher Elsevier Current Trends
  • Copyright Copyright © 2011 Elsevier Ltd
  • ISSN 0952-7915
  • D.O.I. 10.1016/j.coi.2011.08.002
  • Publisher site Get PDF  

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