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Personalised medicine in hypercholesterolaemia: the role of pharmacogenetics in statin therapy a b c d,e Najmeh Ahangari , Mohammad Doosti , Majid Ghayour Mobarhan , Amirhossein Sahebkar , f a,g,h Gordon ...
will become a useful tool in clinical practice. BRIEF RESEARCH REPORT published: 05 January 2022 doi: 10.3389/fphar.2021.679857 The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence ...
association within 5200 participants, we expect that relevant use of pharmacogenetics of statin therapy in clinical care will be limited. We assume that exploring biological mechanisms of statin therapy ...
adherence and ultimately can impede the long‐term effectiveness of statin therapy . There are several identified pharmacogenetic variants that impact statin disposition and adverse events during statin therapy ...
that prospective genotyping for certain variants may be of use in tailoring statin therapy to reduce cardiovascular events and to avoid statin -induced adverse effects. Pharmacogenetics of the Response to Statins ...
with selected drug–gene pairs; however, little is known about how prescribers respond to pharmacogenetic recommendations for statin therapy . We prospectively assessed prescriber interaction with point‐of‐care ...
Over the past decade, pharmacogenetic testing has emerged in clinical practice to guide selected cardiovascular therapies . The most common implementation in practice is CYP2C19 genotyping to predict ...
statin therapy . The recent focus on the pleiotropic effects of statins that are more frequently observed at higher doses and the conclusion drawn from the large statin trials that low-density lipoprotein ...
in Statin Therapy ? Jaideep Patel & Thura Abd & Roger S. Blumenthal & Khurram Nasir & H. Robert Superko Published online: 30 November 2013 Springer Science+Business Media New York 2013 . . Abstract ...
Interindividual variability in response to 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors, or statins , with regard to both efficacy and safety is an obvious target for pharmacogenetic ...
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