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The Cardiovascular Continuum describes a sequence of events from cardiovascular risk factors to end‐stage heart disease . It includes conventional pathologies affecting cardiovascular functions ...
be an independent risk factor for cardiovascular disease throughout the glucose intolerance continuum . Evidence that molecular mechanisms induced by postprandial hyperglycaemia contribute to vascular damage has ...
of nerve function (neuropathy). These complications may result in foot ulceration and eventually amputation of the foot. Vascular diseases in the foot (e.g. diabetic foot) can be divided into three major ...
Background:The relation between vascular risk factors (VRFs) and Alzheimer’s disease (AD) is important due to possible pathophysiological association.Objective:To assess the prevalence of VRFs ...
with persistent diabetic conditions. We have previously shown that, starting at three months of age, pdx1 mutants exhibit not only vascular but also neuro-retinal pathologies manifesting as photoreceptor ...
of cardiac anomalies in AD process. In consequence, reduced cerebral blood flow triggered by cardiac dysfunction further deteriorates vascular dementia and AD pathology . Patients with atrial fibrillation ...
Introduction Diabetes mellitus (DM) are associated with the development of atherosclerosis and increased cardiovascular mortality [1, 2]. The central key pathological role of DM involves metabolic ...
at the mild to moderate stage, including studies with bapineuzumab (AAB-001) and solanezumab (EXPEDITION I, II, III). More recent trials conducted at earlier stages of the Alzheimer’s disease continuum ...
with comorbidities such as history of MI, cerebrovascular disease , revascularization status, diabetes , asthma/chronic obstructive pulmonary disease , or peripheral vascular disease , the anti-anginal efficacy ...
as a sequence of related pathological events. In this model, the progression of cardiovascular diseases starts from risk factors such as hypertension and diabetes leading through coronary artery disease (CAD ...
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