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gene expression post‐ transcriptionally and play important roles in various biological processes. We previously identified miR‐203 as a skin‐ and keratinocyte‐specific microRNA. Moreover, miR‐203 has been ...
members, EBV displays a biphasic life cycle characterized by lytic production of progeny virions and distinct periods of transcriptionally repressed latency [4,5]. EBV latency and reactivation is highly ...
precursors. Surprisingly, although HGG precursors generated endogenous bone morphogenetic protein (BMP) signaling that promoted mitotic arrest under high oxygen tension, this signaling was actively repressed ...
normal human epidermal keratinocytes to model interfollicular human epidermis demonstrate a 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated acceleration of differentiation and increase in gene ...
) as reporter gene . Vector pXP2-CD1 contains luciferase reporter gene under the control of the human cyclin D1 promoter (Herber et al., 1994) kindly donated by Dr Francoise Thierry (Institute Pasteur, Paris ...
% oxygen; 36 h) induces BZLF1 gene expression in human EBV+ Akata B cells and LCLs as well as B95-8 cells. Here, we report that drugs that mimic hypoxia induce lytic EBV infection in some EBV+ epithelial ...
differentiation through transcriptional repression of cellular genes required for differentiation [54,60,61]. To determine if ΔNp63ɑ over-expression reduces EBV lytic reactivation during epithelial cell ...
reactivation in humans . Download: PPT PowerPoint slide PNG larger image TIFF original image Fig 12. LPA induces EBV lytic reactivation through activating either YAP or TAZ in epithelial cells. A) NOKs-Akata ...
and can easily be envisioned to participate in the transient activation or repression of approximately 1,000 genes that are required for wound closure [7]. Circumstantial evidence in support of a role ...
function, the gene targets of AP-1 and the fine molecular mechanisms through which it exerts its transcriptional actions still remain ill-characterized (1). An inherent difficulty for such studies ...
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