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Autoimmune disease, type 1 diabetes, gastritis, systemic lupus erythematosus, thyroiditis, Grave's disease, Hashimoto's disease, Sjogren's syndrome Autoimmunity is, by definition, supposed ...
Autoimmune polyglandular syndrome type I (APS 1 , also called APECED) is an autosomal-recessive disorder that maps to human chromosome 21q22.3 between markers D21S49 and D21S171 by linkage studies. We ...
by Burnet guided many studies that lead to our current understanding of thymic selection. Thus, when the genetic mutation responsible for autoimmune polyglandular syndrome type 1 was mapped to the autoimmune ...
have addressed the association of risk HLA cluster in multiple endocrine diseases, a syndrome referred to as autoimmune polyglandular syndrome type 2 (APS-2). APS-2 is characterized by at least two ...
polyglandular syndrome . The availability of recombinant antigens has permitted structural analysis of the autoepitopes involved in the autoimmune response to 21-hydroxylase in Addison's disease. Our findings ...
WorldCat 6. Weinstock C , Matheis N, Barkia S, et al. . Autoimmune polyglandular syndrome type 2 shows the same HLA class II pattern as type 1 diabetes . Tissue Antigens . 2011 ; 77 : 317 – 324 . Google ...
effects of a single gene defect. In fact, the elucidation of rare monogenic autoimmune syndromes such as autoimmune polyglandular syndrome type 1 (APS1) caused by mutations in autoimmune regulator (AIRE ...
, responsible for autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) syndrome , can lead to ovarian insufficiency. The gene maps to chromosome 21q22.3. More than 40 AIRE gene mutations ...
Summary A single determinant factor for autoimmunity does not exist; disease development probably involves contributions from genetics, the environment and immune dysfunction. Type 1 diabetes ...
stature, and juvenile rheumatoid arthritis in a patient with autoimmune polyglandular syndrome type 1 : case report and brief review of the literature . ISRN Endocrinol . 2011 ; 2011 : 462759 . Google ...
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