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A novel series of imidazo(1,5- a )pyrazines was synthesized and evaluated as corticotropin releasing hormone (CRH) receptor ligands. SAR studies focused primarily on dialkylamino side chain optimization. SAR of the aryl and small alkyl substituents was also explored.

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Synthesis and evaluation of imidazo(1,5- a )pyrazines as corticotropin releasing hormone receptor ligands

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  • Publisher Elsevier
  • Copyright Copyright © 2002 Bristol-Myers Squibb Company
  • ISSN 0960-894X
  • D.O.I. 10.1016/S0960-894X(01)00741-7
  • Publisher site Get PDF  

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