Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!
, February 2004 (© 2004) Phosphorylated Derivatives That Activate or Inhibit Mammalian Adenosine Kinase Provide Insights into the Role of Pentavalent Ions in AK Catalysis 1 1 1,3 1,2 Jae Park, Bhag Singh, Mary ...
that are embedded into a complex signalling network. Adenosine monophosphate‐dependent kinase (AMPK) is activated by energy deprivation and shuts off adenosine 5′‐triphosphate (ATP)‐consuming anabolic processes ...
The enzyme adenosine kinase (AK) plays a key role in the regulation of intracellular and extracellular concentration of adenosine (Ado), which exhibits potent hormonal activity in cardiovascular ...
target for the clinically widely used bisphosphonates and related compounds, which could possibly be exploited for a new therapeutic application. Our structure – activity studies on different AK activators ...
the active site compared to other BY- kinases may allow for structure -based design of specific inhibitors to target Burkholderia cepacia virulence. biomolecules Article Structural and Functional Insights ...
protein kinases ; sheep's red blood cells; DEAE-cellulose. Cyclic adenosine -3~,5'-monophosphate (cAMP) is a highly important intracellular regu- lator in all mammalian tissues so far studied , including ...
diabetes mellitus (T2DM). The aim of this study was to probe the effect of EA on disordered hepatic energy metabolism and the adenosine monophosphate (AMP)- activated protein kinase (AMPK)/ mammalian target ...
in a mammalian system. Overall, similar effects on receptor activation compared to the yeast system were found with mutations located at the EL, but some contradictory effects were observed for mutations located ...
are involved in the pathogenesis of PD. Osmotin is a structural and functional homolog of adiponectin, which regulates the phosphorylation of 5′ adenosine monophosphate- activated protein kinase (AMPK) via ...
diacylglycerol ERK extracellular signal-regulated kinase HSP heat shock protein ICa-L L-type Ca2+ current JNK jun N-terminal kinase KACh, KAdo, KATP acetylcholine- activated , adenosine - activated , ATP-inhibited ...
Access the full text.
Sign up today, get unlimited access with DeepDyve Pro!