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The nicotinic acetylcholine receptor (AChR) is the archetype member of the superfamily of ligand-gated ion channels that mediate fast intercellular communication in response to endogenous ...
The properties of the nicotinic acetylcholine receptor (AChR) are modulated by its lipid microenvironment. Studies of such modulation are hampered by the cell’s homeostatic mechanisms that impede ...
Darsaut TE Ryan SE Effect of membrane lipid composition on the conformational equilibria of the nicotinic acetylcholine receptor J. Biol. Chem. 2000 275 777 784 Google Scholar CrossRef Search ADS PubMed ...
functionally important lipid class for nicotinic acetylcholine receptors are anionic lipids . In our simulations, we have used PS, which which is found only in the intracellular leaflet of neuronal membranes ...
with correct treatment. Discovery of an autosomal dominant form of SHE (ADSHE) was rapidly followed by discovery of the first causal gene, a missense mutant in CHRNA4 that encodes the α4 nicotinic acetylcholine ...
. The neurotransmitter acetylcholine (ACh) is involved in tuning GH secretion, and its GH-stimulatory action has mainly been shown in adults but is not clearly documented during development. ACh, together ...
The nicotinic acetylcholine receptor (AChR) found at the neuromuscular junction is the autoantigen involved in the autoimmune disease myasthenia gravis (MG) (1–3). Owing to its dual importance as a model ...
comorbidities. Cigarette smoke contains nicotine , carbon monoxide, oxidant chemicals, and metals that can damage the endothelium and disrupt erectile processes. For current smokers, smoking abstinence can ...
et al. Anatomy of the antigenic structure of a large membrane autoantigen, the muscle-type nicotinic acetylcholine receptor . Immunol Rev 1998 ; 163 : 89 – 120 . Google Scholar Crossref Search ADS ...
Abstract Plasmalogens, the most prominent ether (phospho) lipids in mammals, are structural components of most cellular membranes. Due to their physicochemical properties and abundance in the central ...
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