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in ventral forebrain specification is underlined by experiments showing that expression of Shh and Nkx2.1 in the basal telencephalon and hypothalamus is reduced in vitamin-A-deficient (VAD) quail embryos [ 9 ...
of transcription (STAT)-3 signaling [14]. In the presence of growth factors , CNTF is also implicated in the self -renewal of forebrain NSCs [51]. Because both CNTF and the receptor for CNTF were expressed in NSs ...
Retinal induction, Forebrain patterning, BMP inhibition, Transforming growth factor β signaling, Sonic Hedgehog signaling Significance Statement Mesenchymal stem cells (MSC) are potent and promising ...
(D-V) patterning of the telencephalon is induced by gradients of diffusible signaling molecules secreted from the surrounding tissues, such as sonic hedgehog (Shh), fibroblast growth factor 8 (FGF8 ...
growth factor –expressing fibroblasts with fetal dopaminergic neuronal cells can potentiate cellular survival and has resulted in enhanced behavioral functions in a rodent model of Parkinson disease.However ...
, and LT, respectively). See also Supporting Information Figure S1. Abbreviations: DRG, dorsal root ganglia; NPC, neural stem/progenitor cell, EGF, epidermal growth factor , FGF2, fibroblast growth factor 2 ...
-triiodo-L-thyronine (T3), fibroblast growth factor (FGF), retinoic acid, taurine, Shh, and Activin A showed increased efficiency of expression of cone opsin (60%) and rhodopsin (18%) by day 45 of culture ...
sonic hedgehog, is able to stimulate motor neuron differentiation from neuroepithelial cells [16]. In addition, HSPG binds to basic fibroblast growth factor (bFGF) and acts as a coreceptor for bFGF ...
ESCs under growth conditions optimal for self -renewal (with LIF and embryonic fibroblast feeder layers). Gpc4gt-1, Gpc4gt-2, and Gpc4Δex3 cells exhibited morphological and growth properties similar ...
. This ES cell-derived neurosphere system enables the efficient derivation of highly neurogenic fibroblast growth factor -responsive NS/PCs with early temporal identities and high cell-fate plasticity. Over ...
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