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Highlights ► We found that extracellular DNA from irradiated cells influences non-irradiated ones. ► ROS and NO production in non-irradiated HUVECs are similar to bystander effect. ► These effects at least partially depend on TLR9 signaling. ► Irradiation-related oxidation of DNA is an important component of bystander effect.

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Role of extracellular DNA oxidative modification in radiation induced bystander effects in human endotheliocytes

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  • Publisher Elsevier
  • Copyright Copyright © 2011 Elsevier B.V.
  • ISSN 0027-5107
  • D.O.I. 10.1016/j.mrfmmm.2011.09.005
  • Publisher site Get PDF  

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