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Neurobehavioral teratogenicity can be reversed with transplantation of neural stem cells. However, the usefulness of this therapy would be greatly enhanced by employing adult stem cells. In pursuit ...
explored the mechanisms underlying neurobehavioral deficits in mouse and avian (chick, Cayuga duck) models. In mice , prenatal heroin exposure (10 mg/kg on gestation days 9‐18) elicited deficits in behaviors ...
Abstract Axonal morphology is a critical determinant of neuronal connectivity, and perturbation of the rate or extent of axonal growth during development has been linked to neurobehavioral deficits ...
Abstract Pregnant Sprague-Dawley rats were given chlorpyrifos (O,O-diethyl-O-[3,5,6-trichloro-2-pyridinyl] phosphorothioate; CPF) in corn oil by gavage from gestation day 6 (GD 6) through lactation ...
OpenURL Placeholder Text WorldCat Billauer-Haimovitch H , Slotkin TA , Dotan S , Langford R , Pinkas A , Yanai J . Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration ...
to provide valuable new insights into chemical toxicity, drug discovery, and human disease using recent advances in forward and reverse genetic techniques coupled with large-scale, high-throughput screening ...
and embryo lethality at the F3 generation following ancestral (P0) bisphenol A exposure (100 µM). However, chemical or RNAi knockdown of the cognate demethylases reversed the effects of BPA on these 2 marks ...
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