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to the bath. Activation of protein kinase C attenuated the adenosine modulation. Taken together, our results argue that activation of A 1 adenosine receptors in cholinergic interneurons reduces N-type Ca 2 ...
effects upon Kv1.3 were mediated via an increase in intracellular cyclic AMP, whereas ROMK1‐ mRNA expression appeared to be regulated by coupling of adenosine A2a‐ receptors to an alternative pathway, which ...
receptors in human colon cancer tissues and in colon cancer cell lines Caco2, DLD1, HT29. mRNA of all adenosine subtypes was detected in cancer tissues and cell lines. At a protein levels low amount of A1 ...
. Mouse ES cells expressed the A1, A2A, A2B, and A3 adenosine receptors (ARs), whose expression levels were increased by NECA and NECA‐induced increase of IL‐6 mRNA expression or secretion level ...
A1R mRNA and protein expression after binding to the signaling molecule gp130. ( C ) Activation of A1R by low levels of adenosine enhances production of local pro-inflammatory cytokines and promotes ...
-analysis and RNAseq replication studies from the frontal cortex were also searched.33 Fig. 1. Open in new tabDownload slide Relative mRNA expression of adenosine kinase (ADK) splice variants ...
at 4 weeks after BCAS (p < 0.05) ( Fig. 6 A). These results demonstrate that the selective depletion of A 2A R in BMDCs resulted in up- regulation of proinflammatory cytokine mRNA expression and down ...
BackgroundCyclic adenosine monophosphate response element binding protein (CREB) is a transcription factor that, on phosphorylation by protein kinases , is activated, and in response, regulates ...
for the treatment of cardiac fibrosis . Front Pharmacol 2017 ; 8 : 243 . Google Scholar Crossref Search ADS PubMed WorldCat Sheth S et al. Adenosine receptors : expression , function and regulation . Int J Mol Sci 2014 ...
in cerebellar granule cells are induced through a novel G protein -coupled receptor mechanism that requires PKA and Src- kinase activity to link E2 to the ERK/MAPK signaling module. Along with stimulating ERK ...
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