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density range, we observed slightly different distributions of CD9 , CD63 and viral RNA over the individual density fractions. This corresponds to previously published work indicating that different EV ...
, and anti- CD9 antibodies by immuno-gold labeling. The surface distribution of EV-specific markers varied between the antibody markers. Immunofluorescent images showed that the majority of EVs express both ...
by the viral oncogenes. Therefore, it is important to uncover crucial cellular targets that are affected by viral E6/E7 oncogene expression and that support the growth of HPV-positive cancer cells. Micro(mi)RNAs ...
to our knowledge of the metastatic processes following tumor cell entry into circulatory compartments. The use of in vivo video microscopy allows for the direct observation of experimental metastasis over ...
including the tetraspanin CD9 , Hsp90 alpha/beta and flotillin [57], [58]. We first analyzed the expression of flotillin, which is enriched in exosomes [58], [59], [60]. Flotillin was expressed in all human ...
characterized as multipotent mesenchymal progenitors expressing pluripotency markers and high self-renewal potential similar to embryonic stem cells, without being tumorigenic or causing any ethical concern [16 ...
; in vitro) and teratoma (in vivo ) formation, and immunocytochemistry. Expression of specific proteins was assessed by western blot. Please see Supporting Information Experimental Procedures for details ...
S2). Conversely, both cultured CD10+ and CD10− adventitial cells expressed CD9 , CD13, CD29, CD73, CD90, and CD105 (Figure 3H, Figure S2). Three markers (CD10, CD34, and CD54) were differentially ...
the enrichment of gene-sets like GSEA (4), use differential gene expression between two groups of cells, and such approach does not solve the purpose of studying heterogeneity of activity of pathways at single ...
be functional (55). These vesicles are also a vehicle for the horizontal transfer of oncogenes, which are internalized by target cells and consequently increase their tumorigenic potential in vivo (56, 57). ABs ...
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