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of the mesolimbic dopamine (DA) system . However, current studies strongly suggest that opiate actions on γ-aminobutyric acid ( GABA )-ergic cells in both the ventral tegmental area (VTA) and the nucleus accumbens (NAcc ...
for the pathophysiology of burns itch by embracing the contribution of the central nervous system in the maintenance of symptoms into a chronic state. The proposed pathophysiological model paves new avenues in burns ...
model of central sleep apnea, we examine the effects of dronabinol, alone and in combination with selective antagonists in conscious rats chronically instrumented to stage sleep and measure cessation ...
neurotransmitter systems in the central nervous system . Animal studies suggest that acamprosate may modulate the effects of alcohol treatment by affecting GABAergic neurotransmission63 and glutamate ...
of voltage-gated calcium ion channels in central nervous system (CNS) tissues.31,–33 Evidence from animal models of nerve damage and persistent pain suggests that the antinociceptive activities of pregabalin ...
learning ability [17]. In mammals including humans, 5-HT is present in central and peripheral nervous systems , the gastrointestinal tract, platelets and other tissues [18]. 5-HT plays important roles in cell ...
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