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. The PEGylated liposomes were decorated with octreotide (OCT) peptide. OCT is an octapeptide analog of somatostatin growth hormone, having affinity for somatostatin receptors, overexpressed on breast cancer cells ...
action of somatostatin analogs ), and expression and localization of SSTRs after treatment were evaluated. We found that PAS was more potent (by 30%‐45%) than OCT in reducing cAMP and cell proliferation ...
of somatostatin analogs , prophylactic cholecystectomy may be offered for patients selected for resection of NETs of the midgut if future treatment with a somatostatin analog ( octreotide or lanreotide) is considered ...
in adrenocortical tumors and effect of a new somatostatin analog SOM230 on hormone secretion in vitro and in ex vivo adrenal cells . J Endocrinol Invest 2011 ; 34 : e131 – e138 . Google Scholar Crossref Search ADS ...
modified from [70]. aArrows indicate affinity of somatostatin analog for specific somatostatin receptor indicated relative to octreotide . Open in new tab Vascular Endothelial Growth Factor and Vascular ...
hormone production. Until recently, standard therapies for treatment of metastatic NETs included somatostatin analogues such as octreotide for hormonal control, hepatic-directed therapy for regional control ...
(SSTRs), and the somatostatin analogs (SSAs) lanreotide and octreotide established in the treatment of NETs effectively relieve hormonal symptoms and suppress tumor growth (2–4). Further ...
useful for the treatment of high-grade NETs. The bifunctional analog could use the NET cell’s unique characteristics (i.e., the expression of somatostatin receptors) to target the ADM antagonist to the NET ...
, including somatostatin analogs (SSAs), molecularly targeted drugs and cytotoxic agents. In addition, peptide receptor radionucleotide therapy has recently been evaluated for the treatment of various NENs. We ...
analogs [10, 11]. Administration of the somatostatin analog octreotide has previously been shown in a clinical study in humans to reduce severe radiation-induced GI toxicity [12]. Octreotide has a short ...
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