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Journals Steroids Volume 76 Issue 4

Research highlights &z.rtrif; Stat3 interacts with progesterone receptor (PR) and modulates PR transcriptional activation in breast cancer cells. &z.rtrif; Stat3 acts as a coactivator of PR on classical PRE target genes (MMTV and Bcl-X). &z.rtrif; Stat3 also acts as a coactivator of PR in PR nonclassical transcriptional mechanism. &z.rtrif; This study provides new insights into the mechanism of action of PR.

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Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer

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  • Publisher Elsevier
  • Copyright Copyright © 2010 Elsevier Inc.
  • ISSN 0039-128X
  • D.O.I. 10.1016/j.steroids.2010.12.008
  • Publisher site Get PDF  

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