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Search ADS PubMed WorldCat 18. Park E.A. , Jerden D.C., Bahouth S.W. 1995 Regulation of phosphoenolpyruvate carboxykinase gene transcription by thyroid hormone involves two distinct binding sites ...
of the animal. In addition, it is also an endocrine organ secreting hormones and cytokines important for other physiological activities of animals such as metabolism, thermal regulation , and reproduction (Galic ...
genes were also annotated with categories related to “ regulation of transcription” (CDK5 Regulatory Subunit Associated Protein 3, Chromodomain-helicase-DNA- binding protein 7, CDC28 Protein Kinase ...
chromatin accessibility and GR binding at glucocorticoid- regulated enhancers and thereby expression of GR target genes . A similar mechanism is likely utilized by many other SUMOylated TFs. MATERIALS ...
, as overexpression of each disrupts stress fibre formation (Zhu et al., 2008). Akt-dependent phosphorylation of KANK1 results in binding of 14-3-3 proteins and negative regulation of RhoA-dependent actin ...
are regulated by complexes of factors interacting with regulatory elements consisting of multiple binding sites. This regulatory network provides a mechanism for the temporal and spatial control of gene ...
and physiologically relevant model system to study the regulation of tissue-specific gene expression. GH4 cells are a highly differentiated cell line which retain cell-specific functions, normal hormonal responses ...
; general and specific. General TFs bind to the core promoter region to assist the docking of RNA polymerase for basal transcription, whereas the specific TFs regulate the transcription of an individual gene ...
was assayed using quantitative PCR and compared with a negative control locus in DHFR gene (DHFR-negCON). Binding efficiencies of E2F5 onto TFPI2 sequence were shown in terms of relative fold changes ...
Drosophila melanogaster cells the transcriptional activity of two copia-like retrotransposons, 412 and 1731, is negatively regulated by 20-hydroxyecdysone, the steroid molting hormone of insects (Becker et al ...
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