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of bioactive compounds and enable the slow release of EO in animals (Vidhyalakshmi et al., 2009). Lipid matrix microencapsulation has been popularly used to deliver bioactive compounds (e.g., EO, organic acids ...
Abstract Objectives Solid lipid nanoparticles (SLNs) are highly susceptible to phagocytosis by reticuloendothelial system (RES). To overcome this problem, a novel hydrogel-coated SLNs structure ...
, will require an optimal dosage protocol (El Hage, Hernandez-Sanabria and Van de Wiele 2017) that can involve novel microencapsulation techniques or even addition into a proper food matrix. DRYING TECHNIQUES ...
, will require an optimal dosage protocol (El Hage, Hernandez-Sanabria and Van de Wiele 2017) that can involve novel microencapsulation techniques or even addition into a proper food matrix. DRYING TECHNIQUES ...
demonstrated poor accumulation of the SLN in the liver within 2 h of administration.[29] In a further investigation, the lipid was varied and the SLNs of SIM were prepared using compritol 888ATO as the lipid ...
dried drug particles are challenging. Novel strategies have been developed and investigated for drug inhalation via DPIs, including microparticles.[8,9] Advanced products include PulmoSphere™ particles ...
in the larger particles as reported by Rizwan et al.[28] Figure 1 Open in new tabDownload slide Morphology of the lipid colloidal systems used in this study as determined by cryo-field emission scanning electron ...
was selected as the lipidic carrier owing to better drug entrapment efficiency and lower particle size of the SLNs prepared using Compritol. Among Brij 78, Tween 80, Tween 40 and Lutrol F-68, Tween 80 ...
was synthesized via carbodiimide chemistry and used as a lipid moiety for the generation of TMX-SLNs. TMX-SLN formulations were optimized by using 4-factor, 3-level rotatable CCD in terms of particle size ...
in the range of 66.22–90.90%, with high encapsulation efficiencies (89.68–97.55%) and mean particle size of 20.68–35.94 µm. Both lipid type and drug-to- lipid ratio significantly affected t50% (P < 0.0001), where ...
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