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to destruction of target cells, inflammation and difficulties with vector readministration. Immune effectors have been identified as CD8+ cytotoxic T lymphocytes , which destroy vector-transduced cells, as well ...
, the lymphocyte appears the least interesting of all the leukocytes—the monotonous sameness of appearance gives no clue to its complex history, its present function or its future; nor can we differentiate between ...
, the lymphocyte appears the least interesting of all the leukocytes—the monotonous sameness of appearance gives no clue to its complex history, its present function or its future; nor can we differentiate between ...
Abstract The identification of regulatory T (Treg) cells was originally based on CD25 expression; however, CD25 is also expressed by activated effector T cells. FoxP3 is a more definitive marker ...
larger image TIFF original image Fig 1. Characterization of lymphocyte populations by flow cytometry. Data is presented from 30 subjects (17 in the SSG arm and 13 in TM arm represented in circles ...
to reverse new-onset type 1 diabetes (T1D) in rat insulin promoter- lymphocytic choriomeningitis virus glycoprotein (RIP-LCMV-GP) mice. RIP-LCMV-GP mice were infected with LCMV- arm to trigger diabetes. On days ...
of interleukin-7 (IL-7) to ICL patients expanded the CD8+ MAIT-cell subset, with maintained responsiveness and effector functions after IL-7 treatment. Conclusions ICL patients maintain normal levels and function ...
CD103,71 then migrate to lymphoid tissues, where they interact with naive lymphocytes to generate primed, effector lymphocytes that preferentially traffic to the gut.72 DCs that contain live bacteria migrate ...
interfering RNAs or siRNAs) function as the RNA effectors of RNAi, and that the cytoplasmic exonuclease Dicer can process long dsRNA into mature siRNAs. Argonaute proteins bind the siRNA, forming the RNA ...
the expression nor function of CD4+ CD25+ cells was affected in those patients. However, anti–CTLA-4 monoclonal antibody therapy, most likely through a direct stimulation of effector T cells, does result ...
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