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, postsynaptic protein that is phosphorylated by protein kinase C, potentiates synaptic transmission in an LTP‐like manner. Here, we report that a Ng mutant that is unable to be phosphorylated cannot potentiate ...
-dependent alteration of synaptic plasticity. In this study, we report that Wip1, a protein phosphatase, is essential for long - term potentiation (LTP) and long - term depression (LTD) processes. Wip1-deletion ...
Abstract | Long - term potentiation (LTP) of synaptic strength occurs during learning and can last for long periods, making it a probable mechanism for memory storage. LTP induction results in calcium entry ...
The mechanisms underlying the induction of synaptic plasticity and the formation of long ‐ term memory involve activation of cell‐signalling cascades and protein modifications such as phosphorylation ...
recordings in the hippocampal CA1 neurons showed that long - term potentiation (LTP) was significantly reduced, whereas long - term depression (LTD) was unaltered in neurabin KO mice. Moreover, increased AMPA ...
as carbohydrate moieties. These functional groups make the protein perform various functions in different environments. PTMs play a crucial role in memory and learning. Phosphorylation of synaptic proteins ...
It is well-known that some kinases which are involved in the induction of synaptic plasticity probably modulate tau phosphorylation . However, how depression of potentiated synaptic strength ...
Long - term potentiation (LTP) of synaptic transmission in the hippocampus is a much-studied example of synaptic plasticity1,2. Although the role of N-methyl-D-aspartate (NMDA) receptors ...
Long term potentiation and long term depression of synaptic responses in the hippocampus are thought to be critical for certain forms of learning and memory, although until recently it has been ...
also been implicated in the regulation of synaptic transmission and properties of plasticity such as long ‐ term potentiation . In a molecular approach, we have analyzed transgenic mice overexpressing ...
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