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in experimental autoimmune encephalomyelitis (EAE), the mouse model of multiple sclerosis. In this study we report that lithium suppresses EAE induced by encephalitogenic interferon -γ (IFN-γ)-producing T helper ...
Glial cells 519 Interferon -c modulates the functional profile of in-vitro-cultured porcine microglia a a a Bart R. Tambuyzer , Christophe Casteleyn , Steven Van Cruchten , b a Peter Ponsaerts ...
nervous system (ENS) in the digestive tract. STING plays a crucial role in the pathway that induces the production of interferon in response to viral infection in the central nervous system (CNS). A new ...
), 129, 1306–1318 Interferon -g inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress 1 2 3 4 4 1 Wensheng Lin, April Kemper, Jeffrey L. Dupree, Heather P ...
underlying these neuropsychiatric symptoms remain largely unknown, and it is as yet unclear how IFNα signalling might influence central nervous system (CNS) function . Aberrant microglia-mediated synaptic ...
The regulatory peptide galanin is broadly distributed in the central - and peripheral nervous systems as well as in non-neuronal tissues, where it exerts its diverse physiological functions via three ...
for wound healing. Neutrophils are the first cells to be activated and recruited to the central nervous system in both injury and disease. However, our understanding of the role these cells play in behavior ...
It is known that the molecules of innate and adaptive immunity can influence the synaptic activity of the central nervous system (CNS). Interferons (IFNs) are commonly used to treat viral ...
expressed in the immune system , in regulating T cell effector functions associated with autoimmune inflammation in the central nervous system (CNS). British Journal of Pharmacology (2008) 153, 271–276; doi ...
transgenic mouse, carrying a cd2–ifnar1 transgene on a interferon ‐α/β receptor 1 null genetic background, thus allowing expression of the interferon ‐α/β receptor 1 and hence, a functional type I interferon ...
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