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and hemorrhage led to rise in the number of neutrophils /monocytes and platelets in the lungs, and a rise in myeloperoxidase (MPO), neutrophil elastase and complement C5a content. While resuscitation with FWB ...
to investigate necroptosis-induced proinflammatory cytokine secretion and subsequent polymorphonuclear neutrophil (PMN) migration and activation in vitro.Results Ultrasound analysis showed that ~70 ...
and septic shock in which protease are thought to play a critical pathophysiological role. Ulinastatin also inhibits neutrophil activation and degranulation responses [5, 6], and hence attenuates ischemia ...
activation and polymorphonuclear neutrophil leukocyte elastase in sepsis . Arch Surg . 1992;127: 1219-1224.Crossref 43. Harm K, Bartfeld KP, Mathew T. Plasma concentrations of granulocytic elastaseα1 ...
damage, and hyperfibrinolysis. In order for a molecule drug to attenuate effectively this response, it would need to have a broad enough spectrum of activity to inhibit multiple pathways and to limit ...
). Cardiopulmonary bypass had little effect on expression of L‐selectin. These results confirm that aprotinin attenuates leukocyte activation during isolated cardiopulmonary bypass. Cardiac surgery causes ...
with increased concentrations of neutrophil elastase , complement (C3d), IL-8, and free radical activity in agreement with the findings of other workers [8,9]. Normothermia may have reasonably been expected ...
depends not only on the type of dialyser but also on whether it is new or reused. Dialyser reuse causes attenuation of complement activation ; PMN lactoferrin or myeloperoxidase release, however ...
A , Ganz T . Inhibition of neutrophil elastase prevents cathelicidin activation and impairs clearance of bacteria from wounds . Blood . 2001 ; 97 : 297 – 304 . Google Scholar Crossref Search ADS PubMed ...
, Blackburn WD. Fixation of C3 to IgG attenuates neutrophil HOCl generation and collagenase activation . J Immunol 1993 ; 151 : 949 – 58 . Google Scholar PubMed OpenURL Placeholder Text WorldCat 45 Valim YML ...
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