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SUMMARY Immune complexes of lipopoly saccharide (LPS) with homologous IgG antibody induces rheumatoid factor ( RF ) predominantly of the IgG class in normal mice, while LPS alone induces mostly IgM RF ...
(Limulus polyphemus hemocyanin conjugated with Ars [Lph-Ars]) resulted in specific autoanti- IgG Fc ( rheumatoid factor ) production . The response was rapid and only anti- IgG of the IgM isotype is found ...
SUMMARY We studied the in vitro production of rheumatoid factor ( RF ) by spleen cells of normal adult mice. IgG RF cross-reactive with rabbit IgG was produced in response to immune complexes of TNP ...
hypothesis regarding the induction and persistence of RF production in rheumatoid arthritis is that the Fc of IgG is somehow altered, rendering it antigenic. In this study, to better understand the derivation ...
Rheumatoid factors ( RF ) have been classically defined as anti- IgG antibodies , usually of the IgM class, found in the sera of people afflicted with rheumatoid arthritis or a number of other autoimmune diseases ...
Administration of 2,4,6‐trinitrophenylated E. coli lipopolysaccharide (TNP‐LPS) complexed with mouse IgG antibody to TNP specifically gave rise to a marked production of rheumatoid ‐like factors ( RF ...
SUMMARY In order to investigate the in vivo role of rheumatoid factor ( RF ), the effects of the administration of human monoclonal (m) IgM- RF and IgG - RF on the development of arthritis in mice were ...
-extractable nuclear antigens, anti-cardiolipin (aCL), anti-β2 glycoprotein I (anti-β2GPI) autoantibodies, rheumatoid factor ( RF ) and anti-cyclic citrullinated peptide (anti-CCP) autoantibodies were investigated ...
investigations, we peripheral blood mononuclear cells via Fc receptors. demonstrated a correlation between RF , PEG-precipitated IgG Rheumatoid factor ( RF ) develop in response to ICs in many levels and induction ...
of RF precursor cells by immune complexes of unrelated antigen. RHEUMATOID FACTOR ( RF ) PRODUCTION DURING ANAMNESTIC IMMUNE RESPONSES IN THE MOUSE III. Activation of RF Precursor Cells Is Induced ...
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