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in quality to in vivo -derived embryos. This is evident in terms of ultrastructure [12], gene expression profiles [13–15], cryotolerance [16], and pregnancy rate after transfer [17]. This difference ...
knowledge of the role of the Wnt, chemokine, MMP and PG pathways in receptivity and early menstrual events. They provide in vivo evidence supporting direct or indirect regulation of many new transcripts ...
, inactivation of progesterone by 20αHSD causes the decrease in serum progesterone necessary for parturition to occur (3). Using mice rendered deficient for the prostaglandin (PG) PGF2α receptor and in vivo ...
and embryos have been extensively used as in vivo model systems for both the meiotic and mitotic cell cycles [1]. In X. laevis G2 phase arrested oocytes, progesterone has been shown to stimulate resumption ...
Abstract Serotonin [5-hydroxytryptamine (5-HT)] is essential to intrauterine development, but its source is debated. We used immunocytochemistry to gauge 5-HT, its biosynthetic enzyme tryptophan ...
Akt signaling in a sex-specific and estrous cycle- dependent manner. Depression is one of the leading causes of morbidity and mortality. Gender differences in the prevalence, incidence and morbidity risk ...
was opposite to that seen in those with PMDD. For healthy women, the rise in estradiol, progesterone , and allopregnanolone levels in the mid luteal phase signaled a decrease in cortical GABA levels ...
significant FLX dose- dependent decreases of LH- and FSK/sub-LH responses are observed as calculated by the areas under the curves (AUC) ( decrease by 25.4–40.7% at 12,5μM; by 39.3–51.9% at 25μM; by 64.2–68 ...
isoforms. Rat CYP2D4 and human CYP2D6, which are the predominant CYP2D isoforms in the brain, possess 21-hydroxylation activity for both progesterone and 17α-hydroxyprogesterone. In rat brain microsomes ...
- dependent apoptosis (Figs. 7K and 7L), paralleling the in vivo findings in NF-κB reporter mice that E2 supplementation decreased Mn-induced expression of EGFP and NOS2 in astrocytes, as well as neuronal ...
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