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Insulin secretion is impaired in type 2 diabetes (T2D). The insulin and glucose responses to central autonomic activation induced by excitation of brain medullary TRH receptors were studied in T2D ...
Physiol Endocrinol Metab 256 : E439 – E444 , 1989 . OpenUrl Abstract / FREE Full Text 27. ↵ Lee KC , Miller RE . The hepatic vagus nerve and the neural regulation of insulin secretion . Endocrinology 117 ...
- secretion from beta-TC6 cells. Clin Res . 1994; 42( 3): A353. 26. Curry DL. Reflex inhibition of insulin secretion : vagus nerve involvement via CNS. Am J Physiol . 1984; 247( 6 Pt 1): E827– E832. Google ...
hyperglycemia and glucose intolerance through increased hepatic gluconeogenesis and impairment of glucose- mediated beta cell insulin secretion (Miller et al., 2016b). Similar to ozone (Bass et al., 2013; Miller ...
, and Prasenjit Mitra. Glucagon-like peptide 1 receptor mediated endosomal cAMP generation promotes glucose stimulated insulin secretion in pancreatic beta cells . Am J Physiol Endocrinol Metab ; published ahead ...
for the regional malfunction of organs in type 2 diabetes, where increased insulin secretion by the pancreas and disturbed glucose metabolism in the liver coincide with an augmented metabolic activity of visceral ...
receptors binding parameters in the corpus striatum to near control values. Studies by Iismaa et al.[8] highlighted cholinergic- mediated insulin secretion by muscarinic M1 and M3 receptor subtypes. Muscarinic ...
receptor for ghrelin, with CCK-AR in vagal afferent neurons. These results indicate that the vagus nerve plays a crucial role in determining peripheral energy balance. The efficiency of ghrelin and CCK ...
Expression Changes in Sham and HV Rats To further understand the impact of the hepatic vagus nerve on mediating ozone effects on the liver, we analyzed mRNA expression changes using global liver mRNA ...
demonstrated a role for the related FA receptor, GPR40, in the regulation of insulin secretion (28). Both GPR120 and GPR40 are Gq-coupled receptors linked to the activation of Akt, MAPK, and/or calcium signaling ...
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